Rohnert Park, CA (PressExposure) July 21, 2009 -- Heroin is one of the many drugs currently used today for recreational purposes. Though it was used in the treatment of acute pain, myocardial infarction, acute pulmonary oedema, and chronic pain, heroin is known today for its recreational use. Long-term use of heroin will then lead to tolerance, which will usually cause repeated and increased dosage of heroin to attain its euphoric effects. Increasing the consumption of heroin will then lead to moderate physical dependence, and severe psychological dependence which often develops into addiction.
Internationally, heroin is controlled under Schedules I and IV of the Single Convention on Narcotic Drugs. It is illegal to manufacture, possess, or sell heroin without a licence in Belgium, Denmark, Germany, Iran, India, the Netherlands, the United States, Australia, Canada, Ireland, Pakistan, the United Kingdom and Swaziland. Even though heroin is very addictive, therapists have assured that heroin addiction is curable. There have been many kinds of heroin addiction treatment used by different therapists. The use of medications such as Levacetylmethadol is one particular treatment often utilized.
Levacetylmethadol (INN), levomethadyl acetate (USAN), Orlaam (trade name) or levo-?-acetylmethadol (LAAM) is a synthetic opioid similar in structure to methadone as heroin addiction treatment. It has a long duration of action due to its active metabolites. It was approved in 1993 by the U.S. Food and Drug Administration for use in heroin addiction treatment. LAAM is indicated as a second-line treatment for heroin addiction treatment and management of opioid dependence if patients fail to respond to drugs like methadone or buprenorphine.
The first dose of LAAM for patients who have not started treatment with methadone is 20-40mg. The first dose for patients who have been receiving methadone will be a little higher than the amount of methadone that was being taken every day, but not more than 120 mg. Afterwards, the dosage may be adjusted as needed. Unlike methadone, which requires daily administration, LAAM is administered three times a week.
* In 2001, Orlaam was removed from the European market due to reports of life threatening ventricular rhythm disorders. * In 2003, Roxane Laboratories, Inc. discontinued Orlaam in the US. * LAAM is not approved for use in Canada.